How Rare Is Septo-Optic Dysplasia?

Is Septo-Optic Dysplasia a disability?

While some children with SOD have normal intelligence, others have learning disabilities.

Most, however, are developmentally delayed due to vision impairment or neurological problems.

Treatment for SOD is symptomatic.

Hormone deficiencies may be treated with hormone replacement therapy..

Can septo-optic dysplasia be cured?

Although there is no cure for this condition, the treatment is directed toward the specific symptoms in each individual. Children with possible SOD must be kept under careful hormonal follow-up, and, if present, hormone deficiencies should be treated with hormone replacement therapy.

Is optic nerve hypoplasia a disability?

Many people with ONH may exhibit additional abnormalities. Delays in the acquisition of skills that require the coordination of mental and muscular activity (psychomotor retardation) are common in infants. Some affected children have normal intelligence and others have learning disabilities and intellectual disability.

Can you be born with optic nerve damage?

What causes optic nerve atrophy? ONA causes include: tumor, trauma, decreased blood supply (ischemia) or oxygen supply (hypoxia) causing swelling, hereditary, hydrocephalus, toxins, infection, and rare degenerative disorders. Onset can be from birth through adulthood.

What is septum pellucidum?

Definition. The septum pellucidum (SP) is a thin membrane located at the midline of the brain between the two cerebral hemispheres, or halves of the brain. It is connected to the corpus callosum — a collection of nerve fibers that connect the cerebral hemispheres.

Can optic nerve hypoplasia be fixed?

There is no medical or surgical treatment for ONH. However, occlusion of the better seeing eye may improve vision in the other eye. Children with significant vision loss in both eyes may benefit from early supportive attention by low vision specialists.

Can you fix optic nerve damage?

Unfortunately, once damaged, the optic nerve cannot be repaired since the damage is irreversible. The optic nerve is composed of nerve fibers that do not possess the ability to regenerate on their own.

Can you get an optic nerve transplant?

There is no such thing as a whole-eye transplant. The optic nerve, which goes directly to the brain, cannot be transplanted; and this nerve is damaged for many people who are blind. The eye transplant would not work without also transplanting the optic nerve.

Is Cushing’s disease considered a disability?

If the symptoms or complications from your Cushing syndrome affect your ability to function at home and/or at work, you may be able to qualify for Social Security disability benefits, including Social Security Disability Insurance (SSDI) and/or Supplemental Security Income (SSI).

Can optic nerve hypoplasia cause blindness?

A child with the Syndrome of Optic Nerve Hypoplasia (ONH), also known as Septo Optic Dysplasia (SOD) or DeMorsiers Syndrome, has under-developed optic nerves. The optic nerves carry messages from the eye to the brain. ONH is the single leading cause of blindness in infants and toddlers.

What does an adrenal crisis feel like?

Acute adrenal crisis is a medical emergency caused by a lack of cortisol. Patients may experience lightheadedness or dizziness, weakness, sweating, abdominal pain, nausea and vomiting, or even loss of consciousness.

What causes hypoplasia?

Enamel hypoplasia caused by environmental factors carries the same symptoms as hereditary enamel hypoplasia, but can be caused by a variety of factors, such as premature birth, malnutrition, bacterial and viral infections, or trauma to newly developing teeth and mouth.

Is CAH an autoimmune disease?

Autoimmune disorders in individuals with CAH have also been reported in a large study of individuals with different forms of disorders of sex development (DSD) [6].

Can you be born without an optic nerve?

Optic nerve hypoplasia (ONH) is a congenital condition in which the optic nerve is underdeveloped (small). Many times, de Morsier’s Syndrome or septo-optic dysplasia (SOD) is associated with ONH, however, it is possible to have ONH without any additional issues like SOD.

Is optic nerve hypoplasia rare?

Prevalence of Optic Nerve Hypoplasia The prevalence of this disease is approximately 1 in 10,000 children, according to the National Organization of Rare Diseases.

How do you get septo-optic dysplasia?

Causes of septo-optic dysplasia Researchers suspect that genetic and other factors during early development may combine to trigger the onset of the condition. The other factors being studied include viral infections, certain medications, and disruption in blood flow to the fetus’ brain at key stages of development.

Does adrenal insufficiency qualify for disability?

Adrenal Gland Disorders are listed in the Social Security Administration’s impairment listing manual (commonly called the “Blue Book”) as conditions that may qualify a person to receive Social Security Disability Insurance or Supplemental Security Income.

What does absence of septum pellucidum mean?

Specifically, a thin membrane called the septum pellucidum is missing from its normal position in the middle of the brain. When it is missing, symptoms may include learning difficulties, behavioral changes, seizures , and changes in vision. Absence of the septum pellucidum is not typically seen as an isolated finding.

What is pituitary hypoplasia?

MalaCards based summary : Pituitary Hypoplasia, also known as hypoplasia of the pituitary gland, is related to congenital hypopituitarism and isolated growth hormone deficiency, type ii.

What is de Morsier syndrome?

Septo-optic dysplasia (SOD), known also as de Morsier syndrome, is a rare congenital malformation syndrome that features a combination of the underdevelopment of the optic nerve, pituitary gland dysfunction, and absence of the septum pellucidum (a midline part of the brain).